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BMCBI
2007
126views more  BMCBI 2007»
14 years 10 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2007
147views more  BMCBI 2007»
14 years 10 months ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...
CORR
2007
Springer
100views Education» more  CORR 2007»
14 years 10 months ago
Identifying statistical dependence in genomic sequences via mutual information estimates
Questions of understanding and quantifying the representation and amount of information in organisms have become a central part of biological research, as they potentially hold th...
H. M. Aktulga, I. Kontoyiannis, L. A. Lyznik, Luka...
NAR
2008
191views more  NAR 2008»
14 years 10 months ago
The BioGRID Interaction Database: 2008 update
The Biological General Repository for Interaction Datasets (BioGRID) database (http://www. thebiogrid.org) was developed to house and distribute collections of protein and genetic...
Bobby-Joe Breitkreutz, Chris Stark, Teresa Reguly,...
GPEM
2007
87views more  GPEM 2007»
14 years 10 months ago
Motility, mixing, and multicellularity
Abstract. A fundamental issue in evolutionary biology is the transition from unicellular to multicellular organisms, and the cellular differentiation that accompanies the increase...
Cristian A. Solari, John O. Kessler, Raymond E. Go...