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BMCBI
2007
143views more  BMCBI 2007»
14 years 10 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2008
158views more  BMCBI 2008»
14 years 10 months ago
Discovering gene annotations in biomedical text databases
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2008
86views more  BMCBI 2008»
14 years 10 months ago
Piecewise multivariate modelling of sequential metabolic profiling data
Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the...
Mattias Rantalainen, Olivier Cloarec, Timothy M. D...
BMCBI
2008
99views more  BMCBI 2008»
14 years 10 months ago
CWRML: representing crop wild relative conservation and use data in XML
Background: Crop wild relatives are wild species that are closely related to crops. They are valuable as potential gene donors for crop improvement and may help to ensure food sec...
Jonathan D. Moore, Shelagh P. Kell, Jose M. Iriond...
BMCBI
2008
78views more  BMCBI 2008»
14 years 10 months ago
Deducing topology of protein-protein interaction networks from experimentally measured sub-networks
Background: Protein-protein interaction networks are commonly sampled using yeast two hybrid approaches. However, whether topological information reaped from these experimentallym...
Ling Yang, Thomas M. Vondriska, Zhangang Han, W. R...