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JIB
2006
106views more  JIB 2006»
15 years 3 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
KES
2008
Springer
15 years 3 months ago
Downsizing Multigenic Predictors of the Response to Preoperative Chemotherapy in Breast Cancer
We present a method for designing efficient multigenic predictors with few probes and its application to the prediction of the response to preoperative chemotherapy in breast cance...
René Natowicz, Roberto Incitti, Roman Rouzi...
110
Voted
NAR
2008
97views more  NAR 2008»
15 years 3 months ago
Database resources of the National Center for Biotechnology Information
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for th...
David L. Wheeler, Tanya Barrett, Dennis A. Benson,...
137
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BMCBI
2005
104views more  BMCBI 2005»
15 years 3 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
113views more  BMCBI 2005»
15 years 3 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
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