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BMCBI
2010
165views more  BMCBI 2010»
13 years 6 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
ICML
1996
IEEE
14 years 7 months ago
Learning Evaluation Functions for Large Acyclic Domains
Some of the most successful recent applications of reinforcement learning have used neural networks and the TD algorithm to learn evaluation functions. In this paper, we examine t...
Justin A. Boyan, Andrew W. Moore
BMCBI
2006
123views more  BMCBI 2006»
13 years 6 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...