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BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2010
112views more  BMCBI 2010»
14 years 10 months ago
A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning
Background: Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in pr...
Patrick Happel, Kerstin Moller, Ralf Kunz, Irmgard...
BMCBI
2010
86views more  BMCBI 2010»
14 years 10 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...
BMCBI
2007
265views more  BMCBI 2007»
14 years 10 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
81views more  BMCBI 2008»
14 years 10 months ago
A perspective for biomedical data integration: Design of databases for flow cytometry
Background: The integration of biomedical information is essential for tackling medical problems. We describe a data model in the domain of flow cytometry (FC) allowing for massiv...
John Drakos, Marina Karakantza, Nicholas C. Zoumbo...