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» Boosting Relational Sequence Alignments
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RECOMB
2004
Springer
16 years 2 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
110
Voted
BMCBI
2008
145views more  BMCBI 2008»
15 years 2 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
120
Voted
JIIS
2006
147views more  JIIS 2006»
15 years 1 months ago
Mining sequential patterns from data streams: a centroid approach
In recent years, emerging applications introduced new constraints for data mining methods. These constraints are typical of a new kind of data: the data streams. In data stream pro...
Alice Marascu, Florent Masseglia
221
Voted
ROCAI
2004
Springer
15 years 7 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
113
Voted
BMCBI
2007
169views more  BMCBI 2007»
15 years 1 months ago
The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats
Background: In Archeae and Bacteria, the repeated elements called CRISPRs for "clustered regularly interspaced short palindromic repeats" are believed to participate in ...
Ibtissem Grissa, Gilles Vergnaud, Christine Pource...