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BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
Deriving enzymatic and taxonomic signatures of metagenomes from short read data
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
Uri Weingart, Erez Persi, Uri Gophna, David Horn
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BMCBI
2008
101views more  BMCBI 2008»
14 years 9 months ago
Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...
BMCBI
2007
160views more  BMCBI 2007»
14 years 9 months ago
Optimization based automated curation of metabolic reconstructions
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
Vinay Satish Kumar, Madhukar S. Dasika, Costas D. ...
CORR
2010
Springer
160views Education» more  CORR 2010»
14 years 9 months ago
Scalable Probabilistic Databases with Factor Graphs and MCMC
Incorporating probabilities into the semantics of incomplete databases has posed many challenges, forcing systems to sacrifice modeling power, scalability, or treatment of relatio...
Michael L. Wick, Andrew McCallum, Gerome Miklau
BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind