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BMCBI
2010
146views more  BMCBI 2010»
14 years 9 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2007
120views more  BMCBI 2007»
14 years 9 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2008
160views more  BMCBI 2008»
14 years 9 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
TVLSI
2002
97views more  TVLSI 2002»
14 years 9 months ago
Techniques for energy-efficient communication pipeline design
The performance of many modern computer and communication systems is dictated by the latency of communication pipelines. At the same time, power/energy consumption is often another...
Gang Qu, Miodrag Potkonjak