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» Building Genetic Networks for Gene Expression Patterns
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123
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GECCO
2004
Springer
169views Optimization» more  GECCO 2004»
15 years 9 months ago
Genetic Programming Neural Networks as a Bioinformatics Tool for Human Genetics
The identification of genes that influence the risk of common, complex diseases primarily through interactions with other genes and environmental factors remains a statistical and ...
Marylyn D. Ritchie, Christopher S. Coffey, Jason H...
134
Voted
GECCO
2005
Springer
180views Optimization» more  GECCO 2005»
15 years 9 months ago
Inference of gene regulatory networks using s-system and differential evolution
In this work we present an improved evolutionary method for inferring S-system model of genetic networks from the time series data of gene expression. We employed Differential Ev...
Nasimul Noman, Hitoshi Iba
148
Voted
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
15 years 3 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
116
Voted
JCB
2006
114views more  JCB 2006»
15 years 3 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
128
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IJKDB
2010
141views more  IJKDB 2010»
15 years 29 days ago
Mining Frequent Boolean Expressions: Application to Gene Expression and Regulatory Modeling
Regulatory network analysis and other bioinformatics tasks require the ability to induce and represent arbitrary boolean expressions from data sources. We introduce a novel framew...
Mohammed Javeed Zaki, Naren Ramakrishnan, Lizhuang...