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» Building Genetic Networks for Gene Expression Patterns
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TCBB
2011
14 years 4 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
BMCBI
2010
172views more  BMCBI 2010»
14 years 4 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm
BIOSYSTEMS
2007
115views more  BIOSYSTEMS 2007»
14 years 9 months ago
Evolving fuzzy rules to model gene expression
This paper develops an algorithm that extracts explanatory rules from microarray data, which we treat as time series, using genetic programming (GP) and fuzzy logic. Reverse polis...
Ricardo Linden, Amit Bhaya