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» Building Genetic Networks for Gene Expression Patterns
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BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal
BMCBI
2007
197views more  BMCBI 2007»
14 years 9 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BIODATAMINING
2008
147views more  BIODATAMINING 2008»
14 years 9 months ago
Neural networks for genetic epidemiology: past, present, and future
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
Alison A. Motsinger-Reif, Marylyn D. Ritchie
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GECCO
2006
Springer
202views Optimization» more  GECCO 2006»
15 years 1 months ago
Inference of genetic networks using S-system: information criteria for model selection
In this paper we present an evolutionary approach for inferring the structure and dynamics in gene circuits from observed expression kinetics. For representing the regulatory inte...
Nasimul Noman, Hitoshi Iba
BMCBI
2007
103views more  BMCBI 2007»
14 years 9 months ago
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
Wei Zou, David L. Aylor, Zhao-Bang Zeng