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» Building Genetic Networks for Gene Expression Patterns
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CEC
2009
IEEE
15 years 3 months ago
A model for intrinsic artificial development featuring structural feedback and emergent growth
Abstract--A model for intrinsic artificial development is introduced in this paper. The proposed model features a novel mechanism where growth emerges, rather than being triggered ...
Martin Trefzer, Tüze Kuyucu, Julian Francis M...
93
Voted
HYBRID
2004
Springer
15 years 5 months ago
Modeling Subtilin Production in Bacillus subtilis Using Stochastic Hybrid Systems
The genetic network regulating the biosynthesis of subtilin in Bacillus subtilis is modeled as a stochastic hybrid system. The continuous state of the hybrid system is the concentr...
Jianghai Hu, Wei Chung Wu, Shankar Sastry
88
Voted
BMCBI
2008
115views more  BMCBI 2008»
14 years 11 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
15 years 5 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
84
Voted
CPM
2009
Springer
137views Combinatorics» more  CPM 2009»
15 years 6 months ago
The Structure of Level-k Phylogenetic Networks
Evolution is usually described as a phylogenetic tree, but due to some exchange of genetic material, it can be represented as a phylogenetic network which has an underlying tree st...
Philippe Gambette, Vincent Berry, Christophe Paul