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» Building Genetic Networks for Gene Expression Patterns
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RECOMB
2003
Springer
15 years 10 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
115
Voted
GECCO
2003
Springer
124views Optimization» more  GECCO 2003»
15 years 2 months ago
Study Diploid System by a Hamiltonian Cycle Problem Algorithm
Complex representation in Genetic Algorithms and pattern in real problems limits the effect of crossover to construct better pattern from sporadic building blocks. Instead of intro...
Dong Xianghui, Ruwei Dai
BMCBI
2002
214views more  BMCBI 2002»
14 years 9 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2008
166views more  BMCBI 2008»
14 years 9 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...