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» Building Large Knowledge Bases in Molecular Biology
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CIBCB
2005
IEEE
15 years 3 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
BMCBI
2007
155views more  BMCBI 2007»
14 years 9 months ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
RECOMB
2010
Springer
14 years 11 months ago
Leveraging Sequence Classification by Taxonomy-Based Multitask Learning
In this work we consider an inference task that biologists are very good at: deciphering biological processes by bringing together knowledge that has been obtained by experiments u...
Christian Widmer, Jose Leiva, Yasemin Altun, Gunna...
ISBI
2008
IEEE
15 years 4 months ago
Unsupervised segmentation of cell nuclei using geometric models
Fluorescent microscopy of biological samples allows noninvasive screening of specific molecular events in-situ. This approach is useful for investigating intricate signalling path...
Shaun Fitch, Trevor Jackson, Peter Andras, Craig R...
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...