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» Building Large Knowledge Bases in Molecular Biology
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BMCBI
2010
201views more  BMCBI 2010»
14 years 10 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
BCB
2010
140views Bioinformatics» more  BCB 2010»
14 years 4 months ago
Guiding belief propagation using domain knowledge for protein-structure determination
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Ameet Soni, Craig A. Bingman, Jude W. Shavlik
NAACL
2007
14 years 11 months ago
Unsupervised Natural Language Processing Using Graph Models
In the past, NLP has always been based on the explicit or implicit use of linguistic knowledge. In classical computer linguistic applications explicit rule based approaches prevai...
Chris Biemann
ALMOB
2008
112views more  ALMOB 2008»
14 years 10 months ago
Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
BMCBI
2008
152views more  BMCBI 2008»
14 years 10 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...