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» Building Large Knowledge Bases in Molecular Biology
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BMCBI
2006
86views more  BMCBI 2006»
14 years 9 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BMCBI
2005
153views more  BMCBI 2005»
14 years 9 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
ASIAN
2005
Springer
115views Algorithms» more  ASIAN 2005»
15 years 3 months ago
Practical Ontology Systems for Enterprise Application
One of the main challenges in building enterprise applications has been to balance between built-in functionality and domain/scenario-specific customization. The lack of formal way...
Dongkyu Kim, Sang-goo Lee, Junho Shim, Jonghoon Ch...
NAR
2006
71views more  NAR 2006»
14 years 9 months ago
TSEMA: interactive prediction of protein pairings between interacting families
An entire family of methodologies for predicting protein interactions is based on the observed fact that families of interacting proteins tend to have similar phylogenetic trees d...
José M. G. Izarzugaza, David de Juan, Carle...
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...