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IJLIT
2010
67views more  IJLIT 2010»
14 years 10 months ago
Interoperability-Centric Problems: New Challenges and Legal Solutions
Whereas abandonment of detailed regulation is widely asserted to be the true way along with the fluctuations of the business models and emergence of IP-based services, there are s...
Turgut Ayhan Beydogan
BMCBI
2010
100views more  BMCBI 2010»
14 years 9 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
BMCBI
2010
137views more  BMCBI 2010»
14 years 6 months ago
The ancient history of the structure of ribonuclease P and the early origins of Archaea
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
Feng-Jie Sun, Gustavo Caetano-Anollés
BMCBI
2010
145views more  BMCBI 2010»
14 years 6 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...
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BMCBI
2010
144views more  BMCBI 2010»
14 years 6 months ago
Optimizing Transformations for Automated, High Throughput Analysis of Flow Cytometry Data
Background: In a high throughput setting, effective flow cytometry data analysis depends heavily on proper data preprocessing. While usual preprocessing steps of quality assessmen...
Greg Finak, Juan-Manuel Perez, Andrew Weng, Raphae...