Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Background: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do thi...
Background: This paper describes techniques for accelerating the performance of the string set matching problem with particular emphasis on applications in computational proteomic...
Yoginder S. Dandass, Shane C. Burgess, Mark Lawren...