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BMCBI
2008
94views more  BMCBI 2008»
15 years 5 months ago
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C...
BMCBI
2008
95views more  BMCBI 2008»
15 years 5 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
BMCBI
2007
102views more  BMCBI 2007»
15 years 5 months ago
Understanding and using the meaning of statements in a bio-ontology: recasting the Gene Ontology in OWL
The bio-ontology community falls into two camps: first we have biology domain experts, who actually hold the knowledge we wish to capture in ontologies; second, we have ontology s...
Mikel Egaña Aranguren, Sean Bechhofer, Phil...
BMCBI
2008
98views more  BMCBI 2008»
15 years 5 months ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
BMCBI
2008
82views more  BMCBI 2008»
15 years 5 months ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson
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