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162
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BMCBI
2007
15 years 4 months ago
2007
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
154
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BMCBI
2007
15 years 4 months ago
2007
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
148
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BMCBI
2007
15 years 4 months ago
2007
Background: Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. I...
182
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BMCBI
2007
15 years 4 months ago
2007
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
160
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BMCBI
2007
15 years 4 months ago
2007
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...