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165
Voted
BMCBI
2007
15 years 4 months ago
2007
Background: When analyzing microarray gene expression data, missing values are often encountered. Most multivariate statistical methods proposed for microarray data analysis canno...
138
Voted
BMCBI
2007
15 years 4 months ago
2007
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
172
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ESWA
2006
15 years 4 months ago
2006
In recent years, there have been many studies focusing on improving the accuracy of prediction of transmembrane segments, and many significant results have been achieved. In spite...
163
Voted
BMCBI
2007
15 years 4 months ago
2007
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
109
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BMCBI
2007
15 years 4 months ago
2007
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...