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BMCBI
2004
156views more  BMCBI 2004»
15 years 4 months ago
GeneXplorer: an interactive web application for microarray data visualization and analysis
Background: When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to ...
Christian A. Rees, Janos Demeter, John C. Matese, ...
BMCBI
2004
97views more  BMCBI 2004»
15 years 4 months ago
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage pattern
Background: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In t...
Oleg N. Reva, Burkhard Tümmler
BMCBI
2004
141views more  BMCBI 2004»
15 years 4 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
BMCBI
2004
102views more  BMCBI 2004»
15 years 4 months ago
FRAGS: estimation of coding sequence substitution rates from fragmentary data
Background: Rates of substitution in protein-coding sequences can provide important insights into evolutionary processes that are of biomedical and theoretical interest. Increased...
Estienne C. Swart, Winston A. Hide, Cathal Seoighe
BMCBI
2004
134views more  BMCBI 2004»
15 years 4 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
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