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BMCBI
2007
114views more  BMCBI 2007»
14 years 10 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
WWW
2009
ACM
15 years 10 months ago
Matchbox: large scale online bayesian recommendations
We present a probabilistic model for generating personalised recommendations of items to users of a web service. The Matchbox system makes use of content information in the form o...
David H. Stern, Ralf Herbrich, Thore Graepel
BMCBI
2007
265views more  BMCBI 2007»
14 years 10 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2011
14 years 1 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
HEURISTICS
2010
14 years 4 months ago
A large neighbourhood search approach to the multi-activity shift scheduling problem
The challenge in shift scheduling lies in the construction of a set of work shifts, which are subject to specific regulations, in order to cover fluctuating staff demands. This pro...
Claude-Guy Quimper, Louis-Martin Rousseau