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» COCO: Composition Model and Composition Model Implementation
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BMCBI
2008
123views more  BMCBI 2008»
14 years 9 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
BMCBI
2007
125views more  BMCBI 2007»
14 years 9 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
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ALIFE
2006
14 years 9 months ago
Picture This: The State of the Art in Visualization for Complex Adaptive Systems
Visualization has an increasingly important role to play in scientific research. Moreover, visualization has a special role to play within artificial life as a result of the inform...
Seth Bullock, Tom Smith, Jon Bird
NAR
2006
170views more  NAR 2006»
14 years 9 months ago
The UCSC Genome Browser Database: update 2006
The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major m...
Angela S. Hinrichs, Donna Karolchik, Robert Baerts...