62 search results - page 1 / 13 » CONTRAlign: Discriminative Training for Protein Sequence Ali... |
94
Voted
RECOMB
2006
Springer
16 years 25 days ago
2006
Springer
In this paper, we present CONTRAlign, an extensible and fully automatic framework for parameter learning and protein pairwise sequence alignment using pair conditional random field...
114
Voted
BMCBI
2007
15 years 19 days ago
2007
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
125
Voted
BMCBI
2008
15 years 19 days ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
132
Voted
BIBM
2010
IEEE
14 years 10 months ago
2010
IEEE
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
134
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BMCBI
2011
14 years 7 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...