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IDEAL
2007
Springer
14 years 19 days ago
Discriminating Microbial Species Using Protein Sequence Properties and Machine Learning
Abstract. Much work has been done to identify species-specific proteins in sequenced genomes and hence to determine their function. We assumed that such proteins have specific ph...
Ali Al-Shahib, David Gilbert, Rainer Breitling
BMCBI
2008
146views more  BMCBI 2008»
13 years 6 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
HPDC
2010
IEEE
13 years 7 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
BMCBI
2007
105views more  BMCBI 2007»
13 years 6 months ago
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
Irini A. Doytchinova, Darren R. Flower
RECOMB
2009
Springer
14 years 7 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...