Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
: One of the most important problems in SOC platforms design is that of defining strategies for tuning the parameters of a parameterized system so as to obtain the Pareto-optimal s...
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
Evolutionary relationships among species can be represented by a phylogenetic tree and inferred by optimising some measure of fitness, such as the statistical likelihood of the t...