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APLAS
2007
ACM
15 years 3 months ago
Scalable Simulation of Cellular Signaling Networks
Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
Vincent Danos, Jérôme Feret, Walter F...
BMCBI
2010
84views more  BMCBI 2010»
14 years 11 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
BMCBI
2010
147views more  BMCBI 2010»
14 years 11 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BMCBI
2006
130views more  BMCBI 2006»
14 years 11 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
113
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IDA
2006
Springer
14 years 11 months ago
Backward chaining rule induction
Exploring the vast number of possible feature interactions in domains such as gene expression microarray data is an onerous task. We describe Backward-Chaining Rule Induction (BCR...
Douglas H. Fisher, Mary E. Edgerton, Zhihua Chen, ...