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» Causal reasoning on biological networks: interpreting transc...
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BIOINFORMATICS
2012
13 years 19 days ago
Causal reasoning on biological networks: interpreting transcriptional changes
d Abstract) Leonid Chindelevitch1 , Daniel Ziemek1, , Ahmed Enayetallah2 , Ranjit Randhawa1 , Ben Sidders3 , Christoph Brockel4 , and Enoch Huang1 1 Computational Sciences Center o...
Leonid Chindelevitch, Daniel Ziemek, Ahmed Enayeta...
78
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BMCBI
2007
122views more  BMCBI 2007»
14 years 10 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2005
189views more  BMCBI 2005»
14 years 10 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
92
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BMCBI
2011
14 years 1 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf
BMCBI
2007
152views more  BMCBI 2007»
14 years 10 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim