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BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
14 years 10 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
BMCBI
2010
14 years 10 months ago
2010
Background: Computational identification of blood-secretory proteins, especially proteins with differentially expressed genes in diseased tissues, can provide highly useful inform...
BMCBI
2010
2010
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
14 years 10 months ago
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
BMCBI
2010
14 years 10 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2010
14 years 10 months ago
2010
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...