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» Challenges for knowledge discovery in biology
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117
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ISMB
1994
15 years 1 months ago
Representations of Metabolic Knowledge: Pathways
The automatic generation of drawings of metabolic pathways is a challenging problem that depends intimately on exactly what information has been recorded for each pathway, and on ...
Peter D. Karp, Suzanne M. Paley
105
Voted
BMCBI
2006
113views more  BMCBI 2006»
15 years 16 days ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
110
Voted
SCFBM
2008
151views more  SCFBM 2008»
14 years 12 months ago
Wndchrm - an open source utility for biological image analysis
Background: Biological imaging is an emerging field, covering a wide range of applications in biological and clinical research. However, while machinery for automated experimentin...
Lior Shamir, Nikita Orlov, D. Mark Eckley, Tomasz ...
212
Voted
POPL
2008
ACM
16 years 24 days ago
Systems biology, models, and concurrency
Models will play a central role in the representation, storage, manipulation, and communication of knowledge in systems biology. Models capable of fulfilling such a role will like...
Walter Fontana
96
Voted
BMCBI
2010
91views more  BMCBI 2010»
15 years 18 days ago
Ranked retrieval of Computational Biology models
Background: The study of biological systems demands computational support. If targeting a biological problem, the reuse of existing computational models can save time and effort. ...
Ron Henkel, Lukas Endler, Andre Peters, Nicolas Le...