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» Challenges for knowledge discovery in biology
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97
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BMCBI
2006
127views more  BMCBI 2006»
15 years 16 days ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
EDBT
2012
ACM
257views Database» more  EDBT 2012»
13 years 2 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh
116
Voted
SDM
2011
SIAM
230views Data Mining» more  SDM 2011»
14 years 3 months ago
Multidimensional Association Rules in Boolean Tensors
Popular data mining methods support knowledge discovery from patterns that hold in binary relations. We study the generalization of association rule mining within arbitrary n-ary ...
Kim-Ngan Nguyen, Loïc Cerf, Marc Plantevit, J...
117
Voted
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
15 years 6 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
ICASSP
2007
IEEE
15 years 6 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri