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» Challenges for knowledge discovery in biology
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92
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RECOMB
2005
Springer
16 years 25 days ago
Consensus Folding of Unaligned RNA Sequences Revisited
As one of the earliest problems in computational biology, RNA secondary structure prediction (sometimes referred to as "RNA folding") problem has attracted attention agai...
Vineet Bafna, Haixu Tang, Shaojie Zhang
100
Voted
ISMB
2000
15 years 1 months ago
Genes, Themes, and Microarrays: Using Information Retrieval for Large-Scale Gene Analysis
The immensevolumeof data resulting from DNAmicroarray experiments, accompaniedby an increase in the numberof publications discussing gene-related discoveries, presents a majordata...
Hagit Shatkay, Stephen Edwards, W. John Wilbur, Ma...
91
Voted
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
15 years 6 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
103
Voted
ICTAI
2006
IEEE
15 years 6 months ago
Outlier Detection Using Random Walks
The discovery of objects with exceptional behavior is an important challenge from a knowledge discovery standpoint and has attracted much attention recently. In this paper, we pre...
H. D. K. Moonesinghe, Pang-Ning Tan
102
Voted
ISMDA
2005
Springer
15 years 6 months ago
The Ontological Lens: Zooming in and out from Genomic to Clinical Level
Abstract. Ontology is the talk of the day in the medical informatics comm.unity. Its relevant role in the design and implementation of information systems in health care is now wid...
Domenico M. Pisanelli, Francesco Pinciroli, Marco ...