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» Challenges for knowledge discovery in biology
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BMCBI
2010
109views more  BMCBI 2010»
15 years 19 days ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
101
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IJBRA
2010
116views more  IJBRA 2010»
14 years 11 months ago
Scaling alignment of large ontologies
: In recent years, the number of ontologies shared on the Web has increased dramatically, supporting a growing set of applications such as biological knowledge sharing, enhanced se...
Suzette Stoutenburg, Jugal Kalita, Kaily Ewing, Li...
96
Voted
AAAI
2007
15 years 2 months ago
Biomind ArrayGenius and GeneGenius: Web Services Offering Microarray and SNP Data Analysis via Novel Machine Learning Methods
Analysis of postgenomic biological data (such as microarray and SNP data) is a subtle art and science, and the statistical methods most commonly utilized sometimes prove inadequat...
Ben Goertzel, Cassio Pennachin, Lúcio de So...
119
Voted
BMCBI
2007
158views more  BMCBI 2007»
15 years 19 days ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
TEC
2008
99views more  TEC 2008»
15 years 12 days ago
A Drug Candidate Design Environment Using Evolutionary Computation
Abstract-- This article describes the Candidate Design Environment we developed for efficient identification of promising drug candidates. Developing effective drugs from active mo...
M. Ihsan Ecemis, J. Wikel, C. Bingham, Eric Bonabe...