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» Challenges for knowledge discovery in biology
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EVOW
2010
Springer
15 years 7 months ago
A Local Search Appproach for Transmembrane Segment and Signal Peptide Discrimination
Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Sami Laroum, Dominique Tessier, Béatrice Du...
CMSB
2007
Springer
15 years 6 months ago
Reconstructing Metabolic Pathways by Bidirectional Chemical Search
Abstract. One of the main challenges in systems biology is the establishment of the metabolome: a catalogue of the metabolites and biochemical reactions present in a specific orga...
Liliana Félix, Francesc Rosselló, Ga...
RECOMB
2009
Springer
16 years 1 months ago
Haplotype Inference in Complex Pedigrees
Abstract. Despite the desirable information contained in complex pedigree datasets, analysis methods struggle to efficiently process these datasets. The attractiveness of pedigree ...
Bonnie Kirkpatrick, Javier Rosa, Eran Halperin, Ri...
131
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KDD
2004
ACM
106views Data Mining» more  KDD 2004»
16 years 27 days ago
Early detection of insider trading in option markets
"Inside information" comes in many forms: knowledge of a corporate takeover, a terrorist attack, unexpectedly poor earnings, the FDA's acceptance of a new drug, etc...
Steve Donoho
KDD
2003
ACM
148views Data Mining» more  KDD 2003»
16 years 27 days ago
Mining concept-drifting data streams using ensemble classifiers
Recently, mining data streams with concept drifts for actionable insights has become an important and challenging task for a wide range of applications including credit card fraud...
Haixun Wang, Wei Fan, Philip S. Yu, Jiawei Han