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» Challenges for knowledge discovery in biology
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AIPS
2003
14 years 10 months ago
A Multi-Agent System-driven AI Planning Approach to Biological Pathway Discovery
As genomic and proteomic data is collected from highthroughput methods on a daily basis, subcellular components are identified and their in vitro behavior is characterized. Howev...
Salim Khan, William Gillis, Carl Schmidt, Keith De...
IDA
2008
Springer
14 years 9 months ago
ExpertDiscovery system application for the hierarchical analysis of eukaryotic transcription regulatory regions based on DNA cod
We developed Relational Data Mining approach which allows to overcome essential limitations of the Data Mining and Knowledge Discovery techniques. In the paper the approach was im...
I. V. Khomicheva, Eugenii E. Vityaev, Elena A. Ana...
BMCBI
2006
153views more  BMCBI 2006»
14 years 9 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
ICDT
2003
ACM
150views Database» more  ICDT 2003»
15 years 2 months ago
Bioinformatics Adventures in Database Research
Informatics has helped launch molecular biology into the genomic era. It appears certain that informatics will remain a major contributor to molecular biology in the post-genome er...
Jinyan Li, See-Kiong Ng, Limsoon Wong
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...