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DKE
2008
79views more  DKE 2008»
14 years 9 months ago
Extracting k most important groups from data efficiently
We study an important data analysis operator, which extracts the k most important groups from data (i.e., the k groups with the highest aggregate values). In a data warehousing co...
Man Lung Yiu, Nikos Mamoulis, Vagelis Hristidis
80
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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
14 years 9 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
101views more  BMCBI 2006»
14 years 9 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
BMCBI
2006
153views more  BMCBI 2006»
14 years 9 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2006
160views more  BMCBI 2006»
14 years 9 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
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