524 search results - page 22 / 105 » Challenges of sequencing human genomes |
BMCBI
2010
14 years 12 months ago
2010
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
BMCBI
2005
14 years 11 months ago
2005
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
RECOMB
2006
Springer
16 years 2 days ago
2006
Springer
Micro-indels are small insertion or deletion events (indels) that occur during genome evolution. The study of micro-indels is important, both in order to better understand the unde...
BMCBI
2010
14 years 12 months ago
2010
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
IDEAL
2004
Springer
15 years 5 months ago
2004
Springer
This paper presents an effective core-promoter prediction system on human DNA sequence. The system, named PromSearch, employs a hybrid approach which combines search-by-content met...