524 search results - page 2 / 105 » Challenges of sequencing human genomes |
105
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CSB
2002
IEEE
15 years 4 months ago
2002
IEEE
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
109
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BMCBI
2007
14 years 11 months ago
2007
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
120
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BMCBI
2011
14 years 3 months ago
2011
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
NAR
2006
14 years 11 months ago
2006
The mitochondrial genome, contained in the subcellular mitochondrial network, encodes a small number of peptides pivotal for cellular energy production. Mitochondrialgenesarehighl...
RECOMB
2001
Springer
15 years 4 months ago
2001
Springer
Two different approaches to determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly-funded Human Genome Proje...