524 search results - page 2 / 105 » Challenges of sequencing human genomes |
CSB
2002
IEEE
13 years 11 months ago
2002
IEEE
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
BMCBI
2007
13 years 6 months ago
2007
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
BMCBI
2011
12 years 9 months ago
2011
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
NAR
2006
13 years 6 months ago
2006
The mitochondrial genome, contained in the subcellular mitochondrial network, encodes a small number of peptides pivotal for cellular energy production. Mitochondrialgenesarehighl...
RECOMB
2001
Springer
13 years 10 months ago
2001
Springer
Two different approaches to determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly-funded Human Genome Proje...