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» Characterizations of postman sets
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BMCBI
2005
118views more  BMCBI 2005»
15 years 1 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2005
109views more  BMCBI 2005»
15 years 1 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
BMCBI
2005
250views more  BMCBI 2005»
15 years 1 months ago
FiatFlux - a software for metabolic flux analysis from 13C-glucose experiments
Background: Quantitative knowledge of intracellular fluxes is important for a comprehensive characterization of metabolic networks and their functional operation. In contrast to d...
Nicola Zamboni, Eliane Fischer, Uwe Sauer
141
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BMCBI
2005
94views more  BMCBI 2005»
15 years 1 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
134
Voted
BMCBI
2005
117views more  BMCBI 2005»
15 years 1 months ago
An evaluation of GO annotation retrieval for BioCreAtIvE and GOA
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
Evelyn Camon, Daniel Barrell, Emily Dimmer, Vivian...