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BMCBI
2010
148views more  BMCBI 2010»
14 years 9 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
EnvMine: A text-mining system for the automatic extraction of contextual information
Background: For ecological studies, it is crucial to count on adequate descriptions of the environments and samples being studied. Such a description must be done in terms of thei...
Javier Tamames, Victor de Lorenzo
BMCBI
2010
122views more  BMCBI 2010»
14 years 9 months ago
An automated framework for understanding structural variations in the binding grooves of MHC class II molecules
Background: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition ...
Kalidas Yeturu, Tapani Utriainen, Graham J. L. Kem...
BMCBI
2008
93views more  BMCBI 2008»
14 years 9 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
BMCBI
2008
112views more  BMCBI 2008»
14 years 9 months ago
A simplified approach to disulfide connectivity prediction from protein sequences
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...