2447 search results - page 425 / 490 » Chemical Similarity Searching |
BMCBI
2010
14 years 12 months ago
2010
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
110
click to vote
BMCBI
2008
14 years 12 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2007
14 years 12 months ago
2007
Background: Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as od...
107
click to vote
BMCBI
2010
14 years 12 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
106
click to vote
BMCBI
2007
14 years 12 months ago
2007
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...