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158
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BMCBI
2010
15 years 4 months ago
2010
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
160
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BMCBI
2007
15 years 4 months ago
2007
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
152
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BMCBI
2008
15 years 4 months ago
2008
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
141
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BMCBI
2006
15 years 4 months ago
2006
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
123
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BMCBI
2006
15 years 4 months ago
2006
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...