10 search results - page 2 / 2 » Chromosomal Breakpoint Detection in Human Cancer |
BMCBI
2010
14 years 9 months ago
2010
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
BMCBI
2010
14 years 9 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
ISBRA
2009
Springer
15 years 4 months ago
2009
Springer
Abstract. DNA copy number is the number of replicates of a contiguous segment of DNA on the genome. Copy number alteration (CNA) is a genetic abnormality in which the number of the...
72
Voted
NAR
2010
14 years 4 months ago
2010
Chromosome translocations and gene fusions are frequent events in the human genome and have been found to cause diverse types of tumor. ChimerDB is a knowledgebase of fusion genes...
109
click to vote
BMCBI
2011
14 years 1 months ago
2011
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...