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90
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BMCBI
2010
112views more  BMCBI 2010»
15 years 24 days ago
In silico fragmentation for computer assisted identification of metabolite mass spectra
Background: Mass spectrometry has become the analytical method of choice in metabolomics research. The identification of unknown compounds is the main bottleneck. In addition to t...
Sebastian Wolf, Stephan Schmidt, Matthias Mül...
91
Voted
BMCBI
2010
98views more  BMCBI 2010»
15 years 24 days ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...
86
Voted
BMCBI
2010
74views more  BMCBI 2010»
15 years 24 days ago
A weighted q-gram method for glycan structure classification
Background: Glycobiology pertains to the study of carbohydrate sugar chains, or glycans, in a particular cell or organism. Many computational approaches have been proposed for ana...
Limin Li, Wai-Ki Ching, Takako Yamaguchi, Kiyoko F...
105
Voted
BMCBI
2008
164views more  BMCBI 2008»
15 years 24 days ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
117
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 24 days ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
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