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BMCBI
2004
206views more  BMCBI 2004»
15 years 3 months ago
Combining gene expression data from different generations of oligonucleotide arrays
Background: One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public re...
Kyu Baek Hwang, Sek Won Kong, Steven A. Greenberg,...
BMCBI
2004
150views more  BMCBI 2004»
15 years 3 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
BMCBI
2004
177views more  BMCBI 2004»
15 years 3 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2004
119views more  BMCBI 2004»
15 years 3 months ago
Genome SEGE: A database for 'intronless' genes in eukaryotic genomes
Background: A number of completely sequenced eukaryotic genome data are available in the public domain. Eukaryotic genes are either 'intron containing' or 'intronle...
Meena K. Sakharkar, Pandjassarame Kangueane
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BMCBI
2004
115views more  BMCBI 2004»
15 years 3 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
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