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101
Voted
BMCBI
2010
15 years 2 months ago
2010
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
160
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BMCBI
2007
15 years 2 months ago
2007
Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
114
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BMCBI
2010
15 years 2 months ago
2010
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
138
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BMCBI
2008
15 years 2 months ago
2008
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
132
Voted
BMCBI
2007
15 years 2 months ago
2007
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...