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» Classification of Cell Membrane Proteins
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NAR
2011
207views Computer Vision» more  NAR 2011»
14 years 1 months ago
PSORTdb - an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...
BMCBI
2008
167views more  BMCBI 2008»
14 years 11 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2010
117views more  BMCBI 2010»
14 years 11 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
BIBM
2009
IEEE
156views Bioinformatics» more  BIBM 2009»
15 years 4 months ago
Bayesian Classifier for Anchored Protein Sorting Discovery
—A typical cell has a size of only 10 µm while it contains about a billion proteins. Transportation of these proteins from their synthesis sites to their target locations within...
Fan Zhang, Jianjun Hu
RECOMB
2005
Springer
15 years 11 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz