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» Classification of Cell Membrane Proteins
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NAR
2011
207views Computer Vision» more  NAR 2011»
14 years 8 days ago
PSORTdb - an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...
BMCBI
2008
167views more  BMCBI 2008»
14 years 9 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2010
117views more  BMCBI 2010»
14 years 9 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
BIBM
2009
IEEE
156views Bioinformatics» more  BIBM 2009»
15 years 2 months ago
Bayesian Classifier for Anchored Protein Sorting Discovery
—A typical cell has a size of only 10 µm while it contains about a billion proteins. Transportation of these proteins from their synthesis sites to their target locations within...
Fan Zhang, Jianjun Hu
RECOMB
2005
Springer
15 years 9 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz