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92
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BMCBI
2005
251views more  BMCBI 2005»
14 years 9 months ago
Contextual weighting for Support Vector Machines in literature mining: an application to gene versus protein name disambiguation
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
Tapio Pahikkala, Filip Ginter, Jorma Boberg, Jouni...
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
110
Voted
JIB
2007
172views more  JIB 2007»
14 years 9 months ago
The ABC (Analysing Biomolecular Contacts)-database
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...
Peter Walter, Sam Ansari, Volkhard Helms
BMCBI
2004
97views more  BMCBI 2004»
14 years 9 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
81
Voted
BMCBI
2004
104views more  BMCBI 2004»
14 years 9 months ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...