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» Classification of microarray data using gene networks
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BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2004
132views more  BMCBI 2004»
15 years 4 months ago
Two-stage normalization using background intensities in cDNA microarray data
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
Dankyu Yoon, Sung-Gon Yi, Ju-Han Kim, Taesung Park
IJON
2008
128views more  IJON 2008»
15 years 4 months ago
Independent arrays or independent time courses for gene expression time series data analysis
In this paper we apply three different independent component analysis (ICA) methods, including spatial ICA (sICA), temporal ICA (tICA), and spatiotemporal ICA (stICA), to gene exp...
Sookjeong Kim, Jong Kyoung Kim, Seungjin Choi
JMLR
2010
125views more  JMLR 2010»
14 years 11 months ago
On utility of gene set signatures in gene expression-based cancer class prediction
Machine learning methods that can use additional knowledge in their inference process are central to the development of integrative bioinformatics. Inclusion of background knowled...
Minca Mramor, Marko Toplak, Gregor Leban, Tomaz Cu...
BMCBI
2007
167views more  BMCBI 2007»
15 years 4 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk